Pesquisa | BVS Violência e Saúde

1.

An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.

Borriello, Francesco; Poli, Valentina; Shrock, Ellen; Spreafico, Roberto; Liu, Xin; Pishesha, Novalia; Carpenet, Claire; Chou, Janet; Di Gioia, Marco; McGrath, Marisa E; Dillen, Carly A; Barrett, Nora A; Lacanfora, Lucrezia; Franco, Marcella E; Marongiu, Laura; Iwakura, Yoichiro; Pucci, Ferdinando; Kruppa, Michael D; Ma, Zuchao; Lowman, Douglas W; Ensley, Harry E; Nanishi, Etsuro; Saito, Yoshine; O'Meara, Timothy R; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Dowling, David J; Frieman, Matthew; Elledge, Stephen J; Levy, Ofer; Irvine, Darrell J; Ploegh, Hidde L; Williams, David L; Zanoni, Ivan.

Cell ; 185(4): 614-629.e21, 2022 02 17.

Artigo em Inglês | MEDLINE | ID: mdl-35148840

2.

Training the metaorganism: the microbial counterpart.

King, Irah L; Divangahi, Maziar.

Cell ; 184(3): 574-576, 2021 02 04.

Artigo em Inglês | MEDLINE | ID: mdl-33545033

3.

Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates.

Viant, Charlotte; Weymar, Georg H J; Escolano, Amelia; Chen, Spencer; Hartweger, Harald; Cipolla, Melissa; Gazumyan, Anna; Nussenzweig, Michel C.

Cell ; 183(5): 1298-1311.e11, 2020 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-33125897

4.

Heterogeneous plasma cells and long-lived subsets in response to immunization, autoantigen and microbiota.

Liu, Xin; Yao, Jiacheng; Zhao, Yongshan; Wang, Jianbin; Qi, Hai.

Nat Immunol ; 23(11): 1564-1576, 2022 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-36316480

5.

The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination.

Tomalka, Jeffrey Alan; Pelletier, Adam Nicolas; Fourati, Slim; Latif, Muhammad Bilal; Sharma, Ashish; Furr, Kathryn; Carlson, Kevin; Lifton, Michelle; Gonzalez, Ana; Wilkinson, Peter; Franchini, Genoveffa; Parks, Robert; Letvin, Norman; Yates, Nicole; Seaton, Kelly; Tomaras, Georgia; Tartaglia, Jim; Robb, Merlin L; Michael, Nelson L; Koup, Richard; Haynes, Barton; Santra, Sampa; Sekaly, Rafick Pierre.

Nat Immunol ; 22(10): 1294-1305, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34556879

6.

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.

Saphire, Erica Ollmann; Schendel, Sharon L; Fusco, Marnie L; Gangavarapu, Karthik; Gunn, Bronwyn M; Wec, Anna Z; Halfmann, Peter J; Brannan, Jennifer M; Herbert, Andrew S; Qiu, Xiangguo; Wagh, Kshitij; He, Shihua; Giorgi, Elena E; Theiler, James; Pommert, Kathleen B J; Krause, Tyler B; Turner, Hannah L; Murin, Charles D; Pallesen, Jesper; Davidson, Edgar; Ahmed, Rafi; Aman, M Javad; Bukreyev, Alexander; Burton, Dennis R; Crowe, James E; Davis, Carl W; Georgiou, George; Krammer, Florian; Kyratsous, Christos A; Lai, Jonathan R; Nykiforuk, Cory; Pauly, Michael H; Rijal, Pramila; Takada, Ayato; Townsend, Alain R; Volchkov, Viktor; Walker, Laura M; Wang, Cheng-I; Zeitlin, Larry; Doranz, Benjamin J; Ward, Andrew B; Korber, Bette; Kobinger, Gary P; Andersen, Kristian G; Kawaoka, Yoshihiro; Alter, Galit; Chandran, Kartik; Dye, John M.

Cell ; 174(4): 938-952.e13, 2018 08 09.

Artigo em Inglês | MEDLINE | ID: mdl-30096313

7.

Strength of tonic T cell receptor signaling instructs T follicular helper cell-fate decisions.

Bartleson, Juliet M; Viehmann Milam, Ashley A; Donermeyer, David L; Horvath, Stephen; Xia, Yu; Egawa, Takeshi; Allen, Paul M.

Nat Immunol ; 21(11): 1384-1396, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32989327

8.

Environmental pollutants and the immune response.

Suzuki, Takafumi; Hidaka, Takanori; Kumagai, Yoshito; Yamamoto, Masayuki.

Nat Immunol ; 21(12): 1486-1495, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33046888

9.

TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures.

Tu, Ang A; Gierahn, Todd M; Monian, Brinda; Morgan, Duncan M; Mehta, Naveen K; Ruiter, Bert; Shreffler, Wayne G; Shalek, Alex K; Love, J Christopher.

Nat Immunol ; 20(12): 1692-1699, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31745340

10.

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.

Kanekiyo, Masaru; Joyce, M Gordon; Gillespie, Rebecca A; Gallagher, John R; Andrews, Sarah F; Yassine, Hadi M; Wheatley, Adam K; Fisher, Brian E; Ambrozak, David R; Creanga, Adrian; Leung, Kwanyee; Yang, Eun Sung; Boyoglu-Barnum, Seyhan; Georgiev, Ivelin S; Tsybovsky, Yaroslav; Prabhakaran, Madhu S; Andersen, Hanne; Kong, Wing-Pui; Baxa, Ulrich; Zephir, Kathryn L; Ledgerwood, Julie E; Koup, Richard A; Kwong, Peter D; Harris, Audray K; McDermott, Adrian B; Mascola, John R; Graham, Barney S.

Nat Immunol ; 20(3): 362-372, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30742080

11.

Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin.

Ye, Liang; Schnepf, Daniel; Becker, Jan; Ebert, Karolina; Tanriver, Yakup; Bernasconi, Valentina; Gad, Hans Henrik; Hartmann, Rune; Lycke, Nils; Staeheli, Peter.

Nat Immunol ; 20(5): 593-601, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30886417

12.

Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.

Moin, Syed M; Boyington, Jeffrey C; Boyoglu-Barnum, Seyhan; Gillespie, Rebecca A; Cerutti, Gabriele; Cheung, Crystal Sao-Fong; Cagigi, Alberto; Gallagher, John R; Brand, Joshua; Prabhakaran, Madhu; Tsybovsky, Yaroslav; Stephens, Tyler; Fisher, Brian E; Creanga, Adrian; Ataca, Sila; Rawi, Reda; Corbett, Kizzmekia S; Crank, Michelle C; Karlsson Hedestam, Gunilla B; Gorman, Jason; McDermott, Adrian B; Harris, Audray K; Zhou, Tongqing; Kwong, Peter D; Shapiro, Lawrence; Mascola, John R; Graham, Barney S; Kanekiyo, Masaru.

Immunity ; 55(12): 2405-2418.e7, 2022 12 13.

Artigo em Inglês | MEDLINE | ID: mdl-36356572

13.

Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4⁺ T cells.

Kim, Eunha; Paik, Donggi; Ramirez, Ricardo N; Biggs, Delaney G; Park, Youngjun; Kwon, Ho-Keun; Choi, Gloria B; Huh, Jun R.

Immunity ; 55(1): 145-158.e7, 2022 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-34879222

14.

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.

Escolano, Amelia; Steichen, Jon M; Dosenovic, Pia; Kulp, Daniel W; Golijanin, Jovana; Sok, Devin; Freund, Natalia T; Gitlin, Alexander D; Oliveira, Thiago; Araki, Tatsuya; Lowe, Sarina; Chen, Spencer T; Heinemann, Jennifer; Yao, Kai-Hui; Georgeson, Erik; Saye-Francisco, Karen L; Gazumyan, Anna; Adachi, Yumiko; Kubitz, Michael; Burton, Dennis R; Schief, William R; Nussenzweig, Michel C.

Cell ; 166(6): 1445-1458.e12, 2016 Sep 08.

Artigo em Inglês | MEDLINE | ID: mdl-27610569

15.

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.

Tian, Ming; Cheng, Cheng; Chen, Xuejun; Duan, Hongying; Cheng, Hwei-Ling; Dao, Mai; Sheng, Zizhang; Kimble, Michael; Wang, Lingshu; Lin, Sherry; Schmidt, Stephen D; Du, Zhou; Joyce, M Gordon; Chen, Yiwei; DeKosky, Brandon J; Chen, Yimin; Normandin, Erica; Cantor, Elizabeth; Chen, Rita E; Doria-Rose, Nicole A; Zhang, Yi; Shi, Wei; Kong, Wing-Pui; Choe, Misook; Henry, Amy R; Laboune, Farida; Georgiev, Ivelin S; Huang, Pei-Yi; Jain, Suvi; McGuire, Andrew T; Georgeson, Eric; Menis, Sergey; Douek, Daniel C; Schief, William R; Stamatatos, Leonidas; Kwong, Peter D; Shapiro, Lawrence; Haynes, Barton F; Mascola, John R; Alt, Frederick W.

Cell ; 166(6): 1471-1484.e18, 2016 Sep 08.

Artigo em Inglês | MEDLINE | ID: mdl-27610571

16.

Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.

Burnett, Deborah L; Jackson, Katherine J L; Langley, David B; Aggrawal, Anupria; Stella, Alberto Ospina; Johansen, Matt D; Balachandran, Harikrishnan; Lenthall, Helen; Rouet, Romain; Walker, Gregory; Saunders, Bernadette M; Singh, Mandeep; Li, Hui; Henry, Jake Y; Jackson, Jennifer; Stewart, Alastair G; Witthauer, Franka; Spence, Matthew A; Hansbro, Nicole G; Jackson, Colin; Schofield, Peter; Milthorpe, Claire; Martinello, Marianne; Schulz, Sebastian R; Roth, Edith; Kelleher, Anthony; Emery, Sean; Britton, Warwick J; Rawlinson, William D; Karl, Rudolfo; Schäfer, Simon; Winkler, Thomas H; Brink, Robert; Bull, Rowena A; Hansbro, Philip M; Jäck, Hans-Martin; Turville, Stuart; Christ, Daniel; Goodnow, Christopher C.

Immunity ; 54(12): 2908-2921.e6, 2021 12 14.

Artigo em Inglês | MEDLINE | ID: mdl-34788600

17.

Defining B cell immunodominance to viruses.

Angeletti, Davide; Gibbs, James S; Angel, Matthew; Kosik, Ivan; Hickman, Heather D; Frank, Gregory M; Das, Suman R; Wheatley, Adam K; Prabhakaran, Madhu; Leggat, David J; McDermott, Adrian B; Yewdell, Jonathan W.

Nat Immunol ; 18(4): 456-463, 2017 04.

Artigo em Inglês | MEDLINE | ID: mdl-28192417

18.

B-1 Cells Carry the Memory of Neonatal Immune Imprinting.

Vergani, Stefano; Yuan, Joan.

Immunity ; 53(1): 11-13, 2020 07 14.

Artigo em Inglês | MEDLINE | ID: mdl-32668222

19.

Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses.

Wong, Rachel; Belk, Julia A; Govero, Jennifer; Uhrlaub, Jennifer L; Reinartz, Dakota; Zhao, Haiyan; Errico, John M; D'Souza, Lucas; Ripperger, Tyler J; Nikolich-Zugich, Janko; Shlomchik, Mark J; Satpathy, Ansuman T; Fremont, Daved H; Diamond, Michael S; Bhattacharya, Deepta.

Immunity ; 53(5): 1078-1094.e7, 2020 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-33010224

20.

Central memory CD8⁺ T cells derive from stem-like Tcf7^hi effector cells in the absence of cytotoxic differentiation.

Pais Ferreira, Daniela; Silva, Joana Gomes; Wyss, Tania; Fuertes Marraco, Silvia A; Scarpellino, Léonardo; Charmoy, Mélanie; Maas, Roeltje; Siddiqui, Imran; Tang, Li; Joyce, Johanna A; Delorenzi, Mauro; Luther, Sanjiv A; Speiser, Daniel E; Held, Werner.

Immunity ; 53(5): 985-1000.e11, 2020 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-33128876

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